Fatima Zahra Marhoume
Hassan I University, Morocco
Biography
Abstract
Platelets play pivotal role in primary hemostasis and several cardiovascular diseases (CVD) in athero-thrombotic disease are associated with an increase in blood platelets aggregation. RT extracts was investigated for anti-aggregant activity induced by collagen in vitro and ex vivo by measuring the bleeding time and platelets count. Our finding demonstrated that RT extract showed a significant (P<0.001) inhibition of collagen induced platelets aggregation (1, 48±0, 76, n=3). This results correlate well with data of bleeding time and platelet count. Phytochemical analysis revealed the presence of flavonoids which are may be implicated in this action.